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Welcome to the Department of Physiology and Biophysics!

Welcome to the Department of Physiology and Biophysics! We are over 170 faculty, fellows, students, and staff. Building on strong traditions, we strive to be a world leader in our parallel missions of research, teaching, and service. Our founding chair John Macleod was a future Nobel Laureate, Corneille Heymans was another laureate trained in the Department, and a Lasker Award winner Carl J. Wiggers chaired the Department for a generation. Our research mission benefits from a rare combination of faculty who address important translational problems in physiology and biophysics across a broad spectrum of integration—from the level of the atomic structure of molecules, through living cells and organ systems, and up to the whole organism. The major programmatic foci of our research are cardiovascular, renal, and neuronal function in health and disease. Our educational mission includes a strong PhD-training program as well as a new Master’s program in medical physiology that has attracted considerable interest. Our service mission has a strong impact at the local, national, and international levels.

  • Mission: research, education, service
  • Research Interest: integration of physiology and biophysics from atom to whole organism
  • Former President of FASEB, Secretary General of the IUPS, Co-director of Case’s MSTP
  • Co-home to textbook Medical Physiology

Post-Bacc MS in Medical Physiology Internet Program

Jan. 23, 2014

The Department of Physiology has just announced the option to take our popular Post-Bacc MS in Medical Physiology Program online.  See MSMP Internet Program for online program details.

American Heart Association Summer Training Program

May 27, 2014 - Aug. 1, 2014

The Department of Physiology and Biophysics offers 5 summer research traineeships supported by a recently awarded American Heart Summer Training Grant.  The program is designed for outstanding students with majors in biology, chemistry, physics or related disciplines. Students will carry out a research project under the close guidance of a faculty member for 10 weeks during the summer months (May 27 through Aug. 1, 2014). In general, the program accepts students who have finished their junior year.

Post-Bacc Application Deadline

June 15, 2014

Application deadline: July 15, 2014

July 15, 2014 at midnight is the official deadline for submitting applications for the MS in Medical Physiology Program (Post-Bacc Program). Any online applications that have been initiated at that time will be considered even if it takes the applicant a week or so to complete the application (ex. provide your official transcript, provide GRE, MCAT, or DAT scores, provide your personal statement, provide 3 letters of recommendation).  The admissions committee will review your application once it is complete and all application materials are received.  If you have any questions, please contact Dr. Nosek (, 216-368-3242). Contact us if you need assistance. 

Physiology Annual Picnic

July 11, 2014 3 p.m. - 7 p.m.

The department will be hosting our annual picnic at Squire Valleevue Farm.

Open House for Post-Bacc Medical Physiology Program

May 31, 2014 10:30 a.m.

The Deparment has scheduled an Open House for May 31st.  Prospective students and family members can hear all about our Masters in Medical Physiology program, tour the CWRU campus and department laboratories, and meet faculty and students.  Deadline for registration is May 26th.  Please click here to register online for the event.  Please click here for more information.

2nd Annual Ulrich Hopfer Lecture

May 1, 2014 4 p.m.

The Department of Physiology & Biophysics established this Annual Lecture in honor of the accomplishments Ulrich Hopfer, M.D., Ph.D.  Dr. Hopfer is an internationally recognized scientist whose academic career spans over 35 years here at Case Western Reserve University.  During this time period, he distinguished himself for excellence in research and in teaching. Indeed, postdoctoral fellows, medical students, graduate students, and undergraduates have all benefited from his expertise.  Please join us as we welcome distinguished guest speaker, Christian Aalkjaer, MD., who will be presenting the 2014 Ulrich Hopfer Lecture on Thursday, May 1, 2014 at 4:00pm in the Robbins Building Auditorium, E-501

Congratulation to Prattana Samasilp

March 18, 2014

The Department of Physiology and Biophysics congratulates Dr. Prattana Samasilp, for successfully defending her PhD thesis, "Molecular Control of Fusion Pore Expansion in Mouse Adrenal Chromaffin Cells", on Mar 18th, 2014.

Paper Acceptance: Ross Anderson

March 11, 2014

Congratulations to Ross Anderson on the acceptance of his first paper as first author “Regulation of persistent activity in hippocampal mossy cells by inhibitory synaptic potentials” in Learning and Memory.

Congratulation to Quentin Jamieson

Feb. 24, 2014

The Department of Physiology and Biophysics congratulates Dr. Quentin Jamieson, for successfully defending his PhD thesis, "The Inactivation Mechanisms of Shaker IR and KV2.1 Potassium Channels: Lessons from Pore Mutation", on Feb 24th, 2014.

Congratulation to Sheela Toprani

Feb. 18, 2014

The Department of Physiology and Biophysics congratulates Dr. Sheela Toprani, for successfully defending her PhD thesis, "Mechanisms of Seizure Reduction by Low Frequency Electrical Stimulation", on Feb 18th, 2014.

Post-Baccalaureate Program MS in Medical Physiology

PhD Program Physiology and Biophysics

Upcoming Seminars



Manolis Doxastakis, MSc, PhD
Sept. 8, 2014 4 p.m. - 5 p.m.

School of Medicine E501
Hosted by: Liqun Zhang, PhD



Hiromi Sesaki, PhD
Sept. 15, 2014 4 p.m. - 5 p.m.

School of Medicine E501
Hosted by: Rajesh Ramachandran, PhD


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