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Journal Club

Aya Jishi
Aya Jishi
Oct. 18, 2023 8:45 a.m.
School of Medicine E501
Mentor: Xin Qi, PhD

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JOURNAL CLUB

"Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons"

Science Advances  20 Oct 2021, Vol 7, Issue 43. DOI: 10.1126/sciadv.abg4980
https://www.science.org/doi/10.1126/sciadv.abg4980

Jack H. Brelstaff1 , Matthew Mason1 , Taxiarchis Katsinelos1 ,2, William A. McEwan1, 2, Bernardino Ghetti3, Aviva M. Tolkovsky1*, Maria Grazia Spillantini1

1Department of Clinical Neurosciences, Clifford Allbutt Building, University of Cambridge, Cambridge CB2 0AH, UK. 2UK Dementia Research Institute Cambridge,Island Research Building, University of Cambridge, Cambridge CB2 0AH, UK.3Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis,IN,USA.

*Corresponding author. Email: mgs11@cam.ac.uk (M.G.S.); amtl 004@cam.ac.uk (A.M.T.)